senescence

Code to generate SenSet, a novel human lung senescence cell gene signature.

Quantifying senescence, the easy way.

RNA-seq / Survival analysis of the Nature Communications paper "Small-molecule targeting of kinesin-13 KIF2C enhances double-strand break DNA repair and slows down aging"

Single-cell & bulk RNA-seq analysis of therapy-induced (docetaxel) senescence in human cells

A senescence drug connectivity-mapping pilot that failed its own validation — code, failed tests, and a withdrawn result, published as a negative result.

Control-gene module score for the published SenMayo gene set, with a size-matched random-set bake-off.

Scripts for "Wheat NAC transcription factor NAC5-1 is a positive regulator of senescence" including DAP-seq analysis

Bayesian models linking autumn leaf senescence to carbon assimilation in deciduous broadleaf forests, from Harvard Forest leaf gas exchange to PhenoCam canopy greenness

SenSASP: A Unified, Multi-Layer Database of Senescence and SASP Genes

Reproducible analysis code (R + renv) for the study: Yeast chronological-lifespan extension correlates with human senescence, not longevity (unpublished)

Single-cell RNA-seq analysis of therapy-induced senescence in a mouse model

FAβ-gal: Fluorescence Analysis of β-galactosidase activity

Topological modularity of the SenMayo senescence signature on the human interactome.

This repository contains the code used in the Master's Thesis "Transcriptomic keys of aging" from the Master's Degree in Biomedicine and Molecular Oncology from the University of Oviedo