Rationalized Discovery of Robust antiviral targets Using Genome-scale model Systems

This project focuses on the development of dormant nanoparticles that activate in response to specific biochemical signals, such as those associated with the reactivation of HSV-1 or the presence of disease markers in cancer. These nanoparticles deliver targeted therapies to neutralize viruses or target diseased cells before symptoms appear.

Code and report of ASAP Discovery x OpenADMET challenge (ADMET and Potency).

The Co-culture Efficacy Score (CES) is a quantitative framework for measuring drug activity in complex multicellular systems. It integrates cumulative activity and maximal efficacy into a single interpretable score, separating general toxicity from true effector-mediated cytotoxicity.

Analysis pipeline for detecting molnupiravir-associated mutational signatures in global SARS-CoV-2 data. Includes alignment, QC, Nextclade analysis, UShER phylogenetics, mutational profiling, and exploratory notebooks for visualising patterns across time, countries, and lineages.