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khaled-ghanem/README.md

πŸ‘‹ Hello, I'm Khaled Ghanem

AI & Data Scientist


About Me

AI Engineer and Bioinformatics Researcher with a strong background in Machine Learning, Computer Vision, and multi-omics data analysis.

My work focuses on applying deep learning and statistical modeling to real-world healthcare and genomics problems, including disease prediction, medical image analysis, single-cell transcriptomics, and causal inference.

I’m particularly interested in building AI systems that bridge computational research and clinical impact.


πŸ’» Technical Stack

Mathematics & Statistics

  • Linear Algebra β€’ Probability & Statistics β€’ Statistical Modeling β€’ Hypothesis Testing β€’ Causal Inference

Programming & Engineering

  • Languages: Python β€’ R β€’ SQL β€’ Bash β€’ Git β€’ Docker β€’ Linux

AI & Deep Learning

  • PyTorch β€’ TensorFlow β€’ CNNs (ResNet, VGG, EfficientNet) β€’ Object Detection (YOLOv8) β€’ Image Segmentation (U-Net) β€’ Medical Image Analysis β€’ Transfer Learning β€’ Autoencoders β€’ GANs β€’ Transformers β€’ LLM-based Agents

Machine Learning & Data Science

  • Scikit-learn β€’ XGBoost β€’ LightGBM β€’ Pandas β€’ NumPy β€’ Ensemble Methods β€’ Feature Engineering β€’ Model Interpretability (SHAP) β€’ Hyperparameter Tuning

Cloud & MLOps

  • Platforms: AWS β€’ Huawei Cloud
  • Deployment: Docker β€’ Model deployment (ngrok, Flask & Fast APIs)

Bioinformatics & Omics

  • Workflow & Environment Management: Conda β€’ Nextflow β€’ Snakemake
  • Bioinformatics Tools: FastQC β€’ fastp β€’ Trimmomatic β€’ Kallisto β€’ Bowtie2 β€’ GATK β€’ SAMtools β€’ BCFtools
  • Omics Analysis: RNA-seq β€’ scRNA-seq β€’ WGS β€’ WES β€’ Metabolomics β€’ Multi-omics Integration

πŸ† Featured Projects

🧬 Multi-Omics Causal Inference: Periodontitis & Type 2 Diabetes

Integrated scRNA-seq, DNA methylation, and GWAS data to uncover inflammatory drivers of periodontal-diabetic comorbidity using Mendelian Randomization.

  • Tech: Seurat β€’ Harmony β€’ minfi β€’ limma β€’ TwoSampleMR β€’ STRINGdb
  • Skills: Single-cell analysis, epigenomics, causal inference, network biology

🫁 Pulmonary Nodule Detection & Analysis System

Developed an end-to-end medical imaging pipeline for early lung nodule detection and malignancy analysis from CT scans.

  • Tech: PyTorch β€’ YOLOv8 β€’ U-Net β€’ EfficientNet β€’ OpenCV β€’ LangChain β€’ Gradio
  • Skills: Object detection, medical image segmentation, classification, multimodal AI, report generation

πŸ‘οΈ AI-Based Eye Disease Diagnosis

Built deep learning models for retinal disease classification using fundus images, achieving 99% classification accuracy across 5 disease categories.

  • Tech: TensorFlow β€’ ResNet50 β€’ VGG19 β€’ Flask β€’ Flutter
  • Skills: Computer vision, transfer learning, medical imaging, deployment

🩺 Medical Visual Question Answering (VQA) Assistant

Designed a Vision-Language AI assistant enabling clinicians to query medical images in natural language with context-aware responses.

  • Tech: HuggingFace Transformers β€’ BLIP β€’ LangChain β€’ OpenCV β€’ Gradio
  • Skills: Vision-language models, multimodal AI, LLM agents, medical AI

❀️ Coronary Artery Disease Prediction (IL-18 Biomarker Study)

Developed ML models on clinical and genetic biomarkers for CAD risk prediction, achieving AUC up to 0.956.

  • Tech: Scikit-learn β€’ Random Forest β€’ SVM β€’ SciPy β€’ StatsModels
  • Skills: Predictive modeling, biostatistics, feature engineering, explainable AI

πŸ“¬ Get in Touch


πŸš€ Let's Collaborate!

I'm open to collaborations in:

  • Computational biology & bioinformatics research
  • Multi-omics data analysis and integration
  • Medical AI and disease prediction models
  • Open-source bioinformatics tool development

Feel free to reach out if you'd like to discuss data science, genomics, or AI applications in healthcare!

Pinned Loading

  1. early-cancer-detection early-cancer-detection Public

    Jupyter Notebook

  2. Ocular-Disease-Classification Ocular-Disease-Classification Public

    Train individual CNN models for AMD, DR, Cataract, and Glaucoma diseases using Fundus image dataset.

    Jupyter Notebook

  3. cifar10-classifier-fastapi-streamlit cifar10-classifier-fastapi-streamlit Public

    Python

  4. Variational-Autoencoder-CelebA Variational-Autoencoder-CelebA Public

    Jupyter Notebook

  5. Multi-Omics-Causal-Inference-Periodontitis-Diabetes-Comorbidity Multi-Omics-Causal-Inference-Periodontitis-Diabetes-Comorbidity Public

    R

  6. pulmonary-nodule-detection pulmonary-nodule-detection Public

    Jupyter Notebook