At the crossroads of muscle physiology, respiratory neurophysiology, and biomedical engineering, the NEUromuscular RESpiratory Pathophysiology research group investigates how respiratory muscles function, fail, and recover. Combining multimodal imaging (ultrafast ultrasound, shear wave elastography, molecular imaging), electrophysiology, and tissue-based analysis, we develop quantitative biomarkers that translate physiological insights into actionable metrics and bedside decisions. Our current work drives new diagnostic tools and therapeutic strategies, including muscle-informed assisted ventilation and neurostimulation.
The NEURES group is led by Damien Bachasson and belongs to the joint research unit UMR-S 1158 – Experimental & Clinical Respiratory Neurophysiology based in Paris, France.
To measure, understand, and protect the muscles that drive every breath.
- Nierding, A., Chamalet, E., Similowski, T., Gennisson, J. L. & Bachasson, D. Breath-by-breath parasternal intercostal muscle stiffening tracks inspiratory effort during graded inspiratory threshold loading in humans. J Appl Physiol (1985) (2026). https://doi.org/10.1152/japplphysiol.00160.2026
- Nierding A, Chamalet E, Goettelmann J, Brulon V, Similowski T, Gervais P, Besson FL, Gennisson J-L, and Bachasson D. (2026) First-in-humans evaluation of the metabolic response to loaded breathing across respiratory muscles: a PET-MRI study. Journal of Cachexia, Sarcopenia and Muscle (In revision R2).
- Dres, M., Doorduin, J., Boussouar, S. & Bachasson, D. Advancements in imaging techniques for monitoring the respiratory muscles. Critical Care 29, 110 (2025). https://doi.org/10.1186/s13054-025-05339-1
- Google scholar
- Mutimodal Biomedical Imaging Laboratory – BioMaps (Orsay, France), AP-HP university hospital centre (Paris, France), University of British Columbia, Radboud university medical center (Nijmegen, The Netherlands), Institute of Myology (Paris, France), University of Montevideo (Uruguay)
- labchart_txt_parser — parse LabChart exports
- resp_metrics — compute ventilatory variables from LabChart data