The VCF spec (https://github.com/samtools/hts-specs/blob/master/VCFv4.3.tex) says:
FILTER - filter status: PASS if this position has passed all filters, i.e. a call is made at this position. Otherwise, if the site has not passed all filters, a semicolon-separated list of codes for filters that fail. e.g. “q10;s50”
Some VCF parsers are fussy about this; simple fix:
@@ -196,6 +196,9 @@ while( my $line = $maf_fh->getline ) {
$qual = "." if( !defined $qual or $qual eq "" );
$filter = "." if( !defined $filter or $filter eq "" );
+ # VCF Spec says multiple FILTER tags should be _semicolon_ separated
+ $filter =~ s/,/;/g;
+
# If normal alleles are unset in the MAF (quite common), assume homozygous reference
$n_al1 = $ref if( $n_al1 eq "" );
$n_al2 = $ref if( $n_al2 eq "" );
The VCF spec (https://github.com/samtools/hts-specs/blob/master/VCFv4.3.tex) says:
FILTER - filter status: PASS if this position has passed all filters, i.e. a call is made at this position. Otherwise, if the site has not passed all filters, a semicolon-separated list of codes for filters that fail. e.g. “q10;s50”
Some VCF parsers are fussy about this; simple fix: