I am new to Methylclock and I have a Bisulfite sequencing dataset with Methylation calls.
I am interested in performing the methylclock analysis and checking it looks that it used the models derived from 450K Methyl chip dataset using M-values and beta values.
I want to know how can I convert the Bisulfite sequencing dataset which consists of the coverage, num Cs and num Ts dataset to M-values or beta values.
Thank you.
I am new to Methylclock and I have a Bisulfite sequencing dataset with Methylation calls.
I am interested in performing the methylclock analysis and checking it looks that it used the models derived from 450K Methyl chip dataset using M-values and beta values.
I want to know how can I convert the Bisulfite sequencing dataset which consists of the coverage, num Cs and num Ts dataset to M-values or beta values.
Thank you.