Skip to content

Add AA -> mRNA backtranslation to pVACvector #1411

Description

@susannasiebert

We currently backtranslate the final pVACvector vector peptide sequence from AA -> DNA via a simple lookup table. This process should be improved to take into account all possible codons and pick the most likely one. There are some tools that do so for AA -> mRNA backtranslation:

We want to add AA -> mRNA backtranslation to pVACvector. The existing AA -> DNA backtranslation via codon lookup could then be replaced by using the mRNA sequence and replacing Us with Ts.

Metadata

Metadata

Assignees

No one assigned

    Labels

    No labels
    No labels

    Type

    No type

    Fields

    No fields configured for issues without a type.

    Projects

    No projects

    Relationships

    None yet

    Development

    No branches or pull requests

    Issue actions