diff --git a/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/EncryptDecrypt.cs b/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/EncryptDecrypt.cs
index 09a7e5bb790299..882f61873624b4 100644
--- a/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/EncryptDecrypt.cs
+++ b/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/EncryptDecrypt.cs
@@ -644,7 +644,7 @@ public void RsaDecryptAfterExport()
             Assert.Equal(TestData.HelloBytes, output);
         }
 
-        [Fact]
+        [ConditionalFact(typeof(ImportExport), nameof(ImportExport.Supports16384))]
         public void LargeKeyCryptRoundtrip()
         {
             byte[] output;
diff --git a/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/ImportExport.cs b/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/ImportExport.cs
index 909c455a8134b2..1a911bebd8e88a 100644
--- a/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/ImportExport.cs
+++ b/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/ImportExport.cs
@@ -69,7 +69,7 @@ public static void PaddedExport()
             RSATestHelpers.AssertKeyEquals(diminishedDPParameters, exported);
         }
 
-        [Fact]
+        [ConditionalFact(typeof(ImportExport), nameof(ImportExport.Supports16384))]
         public static void LargeKeyImportExport()
         {
             RSAParameters imported = TestData.RSA16384Params;
@@ -367,6 +367,13 @@ internal static RSAParameters MakePublic(in RSAParameters rsaParams)
 
         private static bool TestRsa16384()
         {
+            if (PlatformDetection.IsAndroid)
+            {
+                // We cannot detect this on Android at the moment. Even attempting to generate or import a 16K RSA key
+                // may leave the error queue in the incorrect state. See https://github.com/google/conscrypt/issues/1507
+                return false;
+            }
+
             try
             {
                 using (RSA rsa = RSAFactory.Create())
diff --git a/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/SignVerify.cs b/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/SignVerify.cs
index c4e33527cdc277..a409e18b677986 100644
--- a/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/SignVerify.cs
+++ b/src/libraries/Common/tests/System/Security/Cryptography/AlgorithmImplementations/RSA/SignVerify.cs
@@ -1022,7 +1022,7 @@ public void VerifyExpectedSignature_PssSha256_RSA2048()
                 modulus2048Signature);
         }
 
-        [Fact]
+        [ConditionalFact(typeof(ImportExport), nameof(ImportExport.Supports16384))]
         public void VerifyExpectedSignature_PssSha256_RSA16384()
         {
             byte[] modulus2048Signature = (
@@ -1098,7 +1098,7 @@ public void VerifyExpectedSignature_PssSha256_RSA16384()
                 modulus2048Signature);
         }
 
-        [Fact]
+        [ConditionalFact(typeof(ImportExport), nameof(ImportExport.Supports16384))]
         public void VerifyExpectedSignature_PssSha384()
         {
             byte[] bigModulusSignature = (