$\color{#d30a7c}{\text{“We are all connected, and the tools of chemistry are merely the keys to the}}$ $\color{#d30a7c}{\text{doors of perception that we have forgotten how to open.” - Alexander Shulgin}}$

UCLA B.S. Biology '22 | Independent Researcher Investigating Neuroplasticity, Epigenetic Modulation, Quantum Biology, and Neurotrophic Factors

• Applied to: UCLA MCDB Master's Program (Fall 2026)
• Important Note: I recently received some bad news that my thyroid nodules are indeterminate (Bethesda III), meaning they may be cancerous. Due to this, I am taking a few weeks to pause my research and focus on my health.
• Health Update: I have resumed my research, just at a slower pace, and have decided to use the data I found to generate a comprehensive systems-level hypothesis to support my systems-biology-thyroid-remodeling repo which you can read about here.

Inspired by my lived experience with autism and a fascinating deep dive into the social polar opposte (Williams Syndrome), I became interested in decoding the biological and nonlinear quantum biochemical frameworks that underlie our dynamic reality. I am an independent biological sciences and topology researcher passionate about understanding neuroplasticity, neurotrophic factors (especially GDNF), non-linear topological dynamics in biological systems, and how the brain can adapt and repair. My independent research focuses on literature synthesis and basic computational approaches to neurotransmitter and growth factor pathways.

• Social Polarity Theory: Analyzing the GTF2I/OXTR genes and oxytocin-vasopressin pathways as a biological "divergence" between Williams Syndrome and ASD.
• The Endogenous Shunt Hypothesis: Modeling overactive INMT pathways and TAAR1 anomalies as a metabolic basis for altered perception in neurodivergence.
• Quantum Biology & Epigenetics:
  • DNA/Microtubule Topology and Biophysics: Investigating piezoelectricity in chromatin and microtubule-mediated phase changes in empathogenic states compared to neurotypical baseline. Also curious how these phase changes differ with the onset of adolescence and adulthood.
  • Quantum Chemistry in Biological Systems: Synthesizing quantum biology, MESP molecular topology, and EZ water dynamics (speculative) into a unified theory to decode the biophysics of empathy and social resonance.
  • Epigenetic Remodeling: Examining MDMA- and 2-CB-assisted therapy as a catalyst for "opening" critical social developmental periods via BDNF and epigenetic modulation.
• Topological Neuroscience: Exploring Topological Data Analysis (TDA) and Persistent Homology to map transitions in high-dimensional neural manifolds during altered states of consciousness and neurodevelopmental shifts.

• Endogenous-Psychedelic-States-ASD-WS-Theory: Investigating the neuropharmacological overlap between Williams Syndrome and ASD. This framework explores the 'Endogenous Empathogen Hypothesis,' analyzing how WS may be characterized by high endogenous phenethylamine sensitivity, whereas ASD is modulated by elevated endogeous tryptamine activity.
  • Computational Skills:
    • Developing automated Bio.Entrez pipelines to systematically mine and cross-reference NCBI literature databases (PubMed/PMC) for targeted neurodevelopmental and genetic frameworks.
    • Engineered a computational molecular mapping tool in Python that processes SMILES strings to calculate and plot electron density gradients as vector fields.
    • Modeled local rotational vector dynamics by mapping the magnitude of the curl of electron density to visualize molecular field perturbations.
    • Developing a Python molecular map that plots the gradient as a vector field of the electron density using SMILES strings, and a subsequent map that plots the magnitude of the curl corresponding to electron density. Also mapped the helical axis of the gradient/curl of substituted phenethylamines to a hypothesized polar coordinate equation.
• Holistic-GDNF-Stimulation-ASD-Theory — A deep dive into GDNF-mediated neuroplasticity, ibogaine, and molecular symmetry.
  • Computational Skills: Developed a recursive Python model to visualize and quantify theorized dendritic re-arborization post GDNF-stimulation.
• systems-biology-thyroid-remodeling: A 14-month longitudinal study characterizing the $Tg/T_{reg}$ Paradox. This research utilizes TI-RADS scoring and paracrine signaling hypotheses to document the transition of high-risk thyroid nodules (TR5 to TR4) via immune-mediated tissue remodeling.

• B.S. in Biology, UCLA, 2022

• Biological literature review & synthesis
• Python/RDKit/Matplotlib/Entrez (basic data handling and modeling)
• LaTeX / Markdown for scientific documentation

• Analyzing direct models of TAAR1 binding pocket topological anomalies (quantum coherence) in models of autism, Williams Syndrome and comparing them to neurotypicals using Quantum Toolbox in Python (QuTip) for high-level quantum simulations.
• Using genome sequencing to quantify the evolutionary domestication hypothesis involving GTF2I and amylase genes (wolves-to-dogs/domesticated humans and Williams Syndrome)
• Phylogenomic modeling of the self-domestication syndrome: Comparing the dendritic branching patterns, perineuronal net tension and flux, GTF2I anomalies, and TAAR-1 alterations in large-scale studies of multiple ASD/WS/neurotypical models to the Geschwind Lab's autism genomic and epigenomic data.
• Developing a machine learning model that predicts how certain molecules interact topologically with receptors, DNA, and GTF2I sites (e.g., how different phenethylamine substitutions might interact with TAAR1/oxytocin signaling expression and induce phonon coupling and non-linear recursive tesseract helical fluctuations that reverberate across these domains).
• Modeling isoquinolone-induced signal stabilization: Probing the transition of recursive tesseract fluctuations into coherent soliton waves. Isoquinilone groups (e.g., in berberine, ibogaine and pharmaceutical analogs) are thought to induce a phase transition via OXTR and TAAR1 stacking interactions, converting recursive tesseract fluctuations into stable soliton waves that propagate to the GTF2I and OXTR loci via DNA intercalation.

$\color{#d30a7c}{\text{☮️ Peace, love, and science!}}$