diff --git a/.github/actions/setup-diffbio/action.yml b/.github/actions/setup-diffbio/action.yml
index 58cb7bf2..0e93b5d4 100644
--- a/.github/actions/setup-diffbio/action.yml
+++ b/.github/actions/setup-diffbio/action.yml
@@ -29,9 +29,9 @@ runs:
         python-version: ${{ inputs.python-version }}
 
     - name: Install uv
-      uses: astral-sh/setup-uv@v1
+      uses: astral-sh/setup-uv@v10.2.0
       with:
-        version: "0.11.3"
+        version: "0.12.21"
         enable-cache: true
         cache-suffix: ${{ inputs.cache-suffix }}